Document Detail

A randomised comparison of polydioxanone (PDS) and polypropylene (Prolene) for abdominal wound closure.
MedLine Citation:
PMID:  3111339     Owner:  NLM     Status:  MEDLINE    
Two hundred and eighty four patients undergoing laparotomy by vertical incision were randomly allocated to closure with interrupted mass sutures of No. 1 polydioxanone (PDS) or No. 1 polypropylene (Prolene). Dehiscence occurred in 0.7% of the PDS group but in 6.4% of the Prolene group (P = 0.018). Wound infection occurred in 8.6% of the PDS group and 15.4% of the Prolene group (P = 0.1). One hundred and ninety patients attended for review at a minimum of one year. Incisional herniation, usually asymptomatic, was present in 11% of each group. Knots were palpable in 2% of the PDS patients but in 12% of the Prolene: wound pain occurred in 12% of the PDS group but in 23% of the Prolene group (P = 0.06). These results suggest that PDS may be useful for abdominal closure.
A E Cameron; C J Parker; E S Field; R C Gray; A P Wyatt
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Annals of the Royal College of Surgeons of England     Volume:  69     ISSN:  0035-8843     ISO Abbreviation:  Ann R Coll Surg Engl     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-08-18     Completed Date:  1987-08-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7506860     Medline TA:  Ann R Coll Surg Engl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  113-5     Citation Subset:  IM    
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MeSH Terms
Abdomen / surgery*
Clinical Trials as Topic
Middle Aged
Postoperative Complications
Random Allocation
Wound Healing / drug effects*
Reg. No./Substance:
0/Plastics; 0/Polyesters; 0/Polypropylenes; 31621-87-1/Polydioxanone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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