Document Detail


The radiological appearances of tuberous sclerosis.
MedLine Citation:
PMID:  10721329     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Tuberous sclerosis is an autosomal dominant disorder often associated with a chromosome 9 abnormality, although up to 60% of cases occur spontaneously. The incidence of the disorder is between 1/100,000 and 1/10,000, and it leads to multiple organ and skeletal abnormalities. The classical triad of epilepsy, mental retardation and adenoma sebaceum defines the syndrome clinically. Other cutaneous associations include shagreen patches, ash leaf-shaped areas of depigmentation, subungual fibromas and café-au-lait spots. This review describes the commoner radiological manifestations of the syndrome, and briefly mentions the rarer associations that have been reported to date.
Authors:
J C Evans; J Curtis
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The British journal of radiology     Volume:  73     ISSN:  0007-1285     ISO Abbreviation:  Br J Radiol     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-03-27     Completed Date:  2000-03-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  91-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiodiagnosis, University Hospital Aintree, Liverpool, Merseyside, UK.
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MeSH Terms
Descriptor/Qualifier:
Echocardiography
Female
Humans
Magnetic Resonance Imaging
Male
Tomography, X-Ray Computed
Tuberous Sclerosis / diagnosis*,  radiography

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