Document Detail

A racing start in life? The hurdles of equine feto-placental pathology.
MedLine Citation:
PMID:  22594040     Owner:  NLM     Status:  MEDLINE    
Significant progress has been made in understanding and monitoring the causes of equine abortion over past decades. However, not all in utero pathology results in abortion. It has long been recognised that some in utero pathology, such as twinning or chronic placentitis, can result in the birth of live but growth-retarded foals and there is historical evidence that birth weight may influence future athletic performance. Clinical experience (e.g. from twins) and experimental studies (pony-Thoroughbred embryo transfer) have highlighted the importance of reduced functional placental area in limiting growth in utero in horses. Many other nonfatal in utero pathologies (e.g. umbilical cord-related circulatory compromise) can potentially affect either placental function or other organ systems. Their influence on the short- and long-term health of the foal and its future athletic performance is in many cases poorly documented or understood. This review summarises the main causes of in utero pathology and reflects on how these may potentially affect the foal if born alive, highlighting the need for long-term studies on this important subject.
A K Foote; S W Ricketts; K E Whitwell
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Equine veterinary journal. Supplement     Volume:  -     ISSN:  -     ISO Abbreviation:  Equine Vet J Suppl     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-05-18     Completed Date:  2012-06-21     Revised Date:  2013-05-16    
Medline Journal Info:
Nlm Unique ID:  9614088     Medline TA:  Equine Vet J Suppl     Country:  United States    
Other Details:
Languages:  eng     Pagination:  120-9     Citation Subset:  IM    
Beaufort Cottage Laboratories, Rossdale and Partners, Newmarket, Suffolk, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Fetal Diseases / pathology,  veterinary*
Horse Diseases / pathology*
Placenta Diseases / pathology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Factors influencing placental development and function in the mare.
Next Document:  Endocrine adaptations in the foal over the perinatal period.