Document Detail


The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence.
MedLine Citation:
PMID:  19787711     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: The Questionnaire for Urinary Incontinence Diagnosis (QUID), a 6-item urinary incontinence (UI) symptom questionnaire, was developed and validated to distinguish stress and urge UI. This study's objective was to evaluate QUID validity and responsiveness when used as a clinical trial outcome measure.
METHODS: Participants enrolled in a multi-center trial of non-surgical therapy (continence pessary, pelvic floor muscle training or combined) for stress-predominant UI and completed baseline and 3-month diaries, the Urinary Distress Inventory (UDI) and QUID. Data from all treatment groups were pooled. QUID internal consistency (Cronbach's alpha) and convergent/discriminant validity (Pearson correlations) were evaluated. Responsiveness to change was assessed with 3-month score outcomes and distribution-based measurements.
RESULTS: Four hundred forty-four women (mean age 50) were enrolled with stress (N = 200) and mixed (N = 244) UI; 344 had 3-month data. Baseline QUID Stress and Urge scores (both scaled 0-15, larger values indicating worse UI) were 8.4 +/- 3.2 and 4.5 +/- 3.3, respectively. Internal consistency of QUID Total, Stress, and Urge scores was 0.75, 0.64 and 0.87, respectively. QUID Stress scores correlated moderately with UDI-Stress scores (r = 0.68, P < 0.0001) and diary stress UI episodes (r = 0.41, P < 0.0001). QUID Urge scores correlated moderately with UDI-Irritative scores (r = 0.68, P < 0.0001) and diary urge UI episodes (r = 0.45, P < 0.0001). Three-month QUID Stress and Urge scores improved (4.1 +/- 3.4 and 2.2 +/- 2.7, both P < 0.0001). QUID Stress score effect size (1.3) and standardized response mean (1.2) suggested a large change after therapy.
CONCLUSION: The QUID has acceptable psychometric characteristics and may be used as a UI outcome measure in clinical trials.
Authors:
Catherine S Bradley; David D Rahn; Ingrid E Nygaard; Matthew D Barber; Charles W Nager; Kimberly S Kenton; Nazema Y Siddiqui; Robert B Abel; Cathie Spino; Holly E Richter
Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Neurourology and urodynamics     Volume:  29     ISSN:  1520-6777     ISO Abbreviation:  Neurourol. Urodyn.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-01     Completed Date:  2010-12-02     Revised Date:  2014-04-23    
Medline Journal Info:
Nlm Unique ID:  8303326     Medline TA:  Neurourol Urodyn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  727-34     Citation Subset:  IM    
Copyright Information:
(c) 2010 Wiley-Liss, Inc.
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Middle Aged
Prospective Studies
Psychometrics
Questionnaires*
Reproducibility of Results
Urinary Incontinence, Stress / diagnosis*,  therapy*
Grant Support
ID/Acronym/Agency:
K23 HD047654/HD/NICHD NIH HHS; K23 HD047654-03/HD/NICHD NIH HHS; U01 HD41249/HD/NICHD NIH HHS; U10 HD054215/HD/NICHD NIH HHS; U10 HD41248/HD/NICHD NIH HHS; U10 HD41250/HD/NICHD NIH HHS; U10 HD41261/HD/NICHD NIH HHS; U10 HD41263/HD/NICHD NIH HHS; U10 HD41267/HD/NICHD NIH HHS; U10 HD41268/HD/NICHD NIH HHS; U10 HD41269/HD/NICHD NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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