| The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence. | |
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MedLine Citation:
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PMID: 19787711 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: The Questionnaire for Urinary Incontinence Diagnosis (QUID), a 6-item urinary incontinence (UI) symptom questionnaire, was developed and validated to distinguish stress and urge UI. This study's objective was to evaluate QUID validity and responsiveness when used as a clinical trial outcome measure. METHODS: Participants enrolled in a multi-center trial of non-surgical therapy (continence pessary, pelvic floor muscle training or combined) for stress-predominant UI and completed baseline and 3-month diaries, the Urinary Distress Inventory (UDI) and QUID. Data from all treatment groups were pooled. QUID internal consistency (Cronbach's alpha) and convergent/discriminant validity (Pearson correlations) were evaluated. Responsiveness to change was assessed with 3-month score outcomes and distribution-based measurements. RESULTS: Four hundred forty-four women (mean age 50) were enrolled with stress (N = 200) and mixed (N = 244) UI; 344 had 3-month data. Baseline QUID Stress and Urge scores (both scaled 0-15, larger values indicating worse UI) were 8.4 +/- 3.2 and 4.5 +/- 3.3, respectively. Internal consistency of QUID Total, Stress, and Urge scores was 0.75, 0.64 and 0.87, respectively. QUID Stress scores correlated moderately with UDI-Stress scores (r = 0.68, P < 0.0001) and diary stress UI episodes (r = 0.41, P < 0.0001). QUID Urge scores correlated moderately with UDI-Irritative scores (r = 0.68, P < 0.0001) and diary urge UI episodes (r = 0.45, P < 0.0001). Three-month QUID Stress and Urge scores improved (4.1 +/- 3.4 and 2.2 +/- 2.7, both P < 0.0001). QUID Stress score effect size (1.3) and standardized response mean (1.2) suggested a large change after therapy. CONCLUSION: The QUID has acceptable psychometric characteristics and may be used as a UI outcome measure in clinical trials. |
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Authors:
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Catherine S Bradley; David D Rahn; Ingrid E Nygaard; Matthew D Barber; Charles W Nager; Kimberly S Kenton; Nazema Y Siddiqui; Robert B Abel; Cathie Spino; Holly E Richter |
Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Neurourology and urodynamics Volume: 29 ISSN: 1520-6777 ISO Abbreviation: Neurourol. Urodyn. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-01 Completed Date: 2010-12-02 Revised Date: 2013-04-26 |
Medline Journal Info:
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Nlm Unique ID: 8303326 Medline TA: Neurourol Urodyn Country: United States |
Other Details:
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Languages: eng Pagination: 727-34 Citation Subset: IM |
Copyright Information:
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(c) 2010 Wiley-Liss, Inc. |
Affiliation:
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Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA. catherine-bradley@uiowa.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Middle Aged Prospective Studies Psychometrics Questionnaires* Reproducibility of Results Urinary Incontinence, Stress / diagnosis*, therapy* |
| Grant Support | |
ID/Acronym/Agency:
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K23 HD047654/HD/NICHD NIH HHS; K23 HD047654-03/HD/NICHD NIH HHS; U01 HD41249/HD/NICHD NIH HHS; U10 HD41248/HD/NICHD NIH HHS; U10 HD41250/HD/NICHD NIH HHS; U10 HD41261/HD/NICHD NIH HHS; U10 HD41263/HD/NICHD NIH HHS; U10 HD41267/HD/NICHD NIH HHS; U10 HD41268/HD/NICHD NIH HHS; U10 HD41269/HD/NICHD NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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