| A qualitative model for aggregation and diffusion of [Formula: see text]-amyloid in Alzheimer's disease. | |
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MedLine Citation:
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PMID: 23014767 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In this paper we present a mathematical model for the aggregation and diffusion of A[Formula: see text] amyloid in the brain affected by Alzheimer's disease, at the early stage of the disease. The model is based on a classical discrete Smoluchowski aggregation equation modified to take diffusion into account. We also describe a numerical scheme and discuss the results of the simulations in the light of the recent biomedical literature. |
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Authors:
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Yves Achdou; Bruno Franchi; Norina Marcello; Maria Carla Tesi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-27 |
Journal Detail:
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Title: Journal of mathematical biology Volume: - ISSN: 1432-1416 ISO Abbreviation: J Math Biol Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7502105 Medline TA: J Math Biol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Laboratoire Jacques-Louis Lions, Sorbonne Paris Cité, Univ. Paris Diderot, UPMC, CNRS, UMR 7598, 75205 , Paris, France, achdou@math.jussieu.fr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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