Document Detail

qnrA in CTX-M-producing Escherichia coli isolates from France.
MedLine Citation:
PMID:  16982788     Owner:  NLM     Status:  MEDLINE    
By PCR, we screened for qnr genes 112 clinical isolates of extended-spectrum beta-lactamase-producing Escherichia coli collected from hospitals in France during 2004. For the first time, 7.7% of CTX-M-producing E. coli isolates presented a plasmid-mediated resistance to quinolones. All strains harbored a qnrA gene located on a sul1-type class 1 integron with similar structure to the In36 integron.
Jean-Philippe Lavigne; Hélène Marchandin; Julien Delmas; Nicole Bouziges; Evelyne Lecaillon; Laurent Cavalie; Hélène Jean-Pierre; Richard Bonnet; Albert Sotto
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-09-18
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  50     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-23     Completed Date:  2007-01-04     Revised Date:  2010-09-15    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4224-8     Citation Subset:  IM    
Laboratoire Universitaire d'Antibiologie, UFR de Médecine, Avenue Kennedy, 30908 Nîmes Cedex 02, France.
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MeSH Terms
Anti-Infective Agents / pharmacology
Drug Resistance, Bacterial / genetics
Escherichia coli / drug effects,  enzymology*,  isolation & purification*
Genes, Bacterial*
Microbial Sensitivity Tests
Nalidixic Acid / pharmacology
Plasmids / genetics
Polymerase Chain Reaction
Quinolones / pharmacology
beta-Lactamases / biosynthesis*
Reg. No./Substance:
0/Anti-Infective Agents; 0/Quinolones; 389-08-2/Nalidixic Acid; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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