Document Detail

Is pulse synchronized pneumotonometry more reproducible than routine pneumotonometry and more in agreement with Goldmann applanation tonometry?
MedLine Citation:
PMID:  17415689     Owner:  NLM     Status:  MEDLINE    
PURPOSE: This study compared the variability of intraocular pressure (IOP) measurements taken with pulse synchronized pneumotonometry (PNT) and with routine PNT (without pulse synchronization) and evaluated the agreement between PNT and Goldmann applanation tonometry (GAT). METHODS: In this prospective study, 148 eyes from 78 patients were enrolled. Patients were randomized into two groups. In the first group (A), the sequence of measurements was pulse synchronized PNT, routine PNT, and GAT. In the second group (B), the sequence of measurements was routine PNT, pulse synchronized PNT, and GAT. The mean of three measurements was averaged for PNT and GAT. All the measurements were performed by the same investigator, who was masked to GAT measurements. The mean IOP measurements and intrapatient standard deviations among the three tonometers were compared using analysis of variance measurement. Bland & Altman plots were used to assess the agreement between PNT and GAT. RESULTS: The variability of IOP measurements taken with pulse synchronized PNT was significantly lower than with routine PNT in both groups (1.2+/-0.7 vs 1.3+/-0.7 mmHg in group A and 1.1+/-0.9 vs 1.3+/-1.0 mmHg in group B [p<0.001], respectively). PNT measurements with and without pulse synchronization were on average +/-2 mmHg higher than GAT measurements in both groups (p<0.001). The 95% limits of agreement between PNT and GAT varied between -3.8 and 8.5 mmHg. CONCLUSIONS: Pulse synchronized PNT gives more reproducible measurements than routine PNT. The agreement between PNT and GAT is poor.
A-S Lafaut; L Van Malderen; T Zeyen
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  17     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2007 Mar-Apr
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  178-82     Citation Subset:  IM    
Department of Ophthalmology, University Hospitals Leuven, 3000 Leuven, Belgium.
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MeSH Terms
Aged, 80 and over
Glaucoma / metabolism
Intraocular Pressure / physiology*
Middle Aged
Prospective Studies
Reproducibility of Results
Tonometry, Ocular / methods*

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