Document Detail


A prototype device for non-invasive continuous monitoring of intracerebral hemorrhage.
MedLine Citation:
PMID:  23261653     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A prototype for a non-invasive, real-time, monitoring device was developed to detect changes in the brain secondary to disease or injury such as intracerebral hemorrhage (ICH). The eventual goal is a non-invasive, real time sensor that can alert the clinician to alterations in the comatose patient's brain resulting from hemorrhage, seizure or stroke. In this work, a 400MHz electromagnetic (EM) signal was transmitted with an antenna (T), incident on a 'brain gel'in-vitro ICH model, and received by a receiving (R) antenna. Changes in the received signal were found to be induced by the presence of blood. The received power (P(R)) was found to be a linear function of the cross sectional area of blood, as measured normal to the incident wave. In addition, the sensor was able to detect as little as 1ml of blood in this 1000ml in-vitro model.
Authors:
Joseph J Korfhagen; Madhuvanthi A Kandadai; Joseph F Clark; Opeolu A Adeoye; George J Shaw
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-19
Journal Detail:
Title:  Journal of neuroscience methods     Volume:  -     ISSN:  1872-678X     ISO Abbreviation:  J. Neurosci. Methods     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7905558     Medline TA:  J Neurosci Methods     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier B.V.
Affiliation:
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267; Department of Neuroscience, University of Cincinnati, Cincinnati, OH 45267.
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