Document Detail


A proteomics view of programmed cell death mechanisms during host-parasite interactions.
MedLine Citation:
PMID:  21843666     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Protozoan parasites are responsible for an impressive disease burden in developing and less-developed countries. The development of vaccines and effective new therapies for dealing with these organisms are among the main gaps to be filled in the control of protozoan parasite diseases. Programmed cell death (PCD) pathways have gained attention in recent years because they comprise complex signalling pathways that can be explored for therapeutic developments. In addition, high-resolution proteomics approaches offer the opportunity to determine protein patterns associated with either cell survival or cell death. This review will focus on proteomics studies of PCD mechanisms during host-protozoan parasite interactions.
Authors:
Patricia Cuervo; Nilma Fernandes; Jose Batista de Jesus
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-6
Journal Detail:
Title:  Journal of proteomics     Volume:  -     ISSN:  1876-7737     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101475056     Medline TA:  J Proteomics     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier B.V. All rights reserved.
Affiliation:
Laboratório de Pesquisa em Leishmaniose, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ, Brazil.
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