Document Detail


The prostatic acid phosphatase (ACPP) gene is localized to human chromosome 3q21-q23.
MedLine Citation:
PMID:  8244395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Human prostatic acid phosphatase (ACPP) has been used as a diagnostic marker for prostate cancer. It is synthesized under androgen regulation and secreted by the epithelial cells of the prostate gland. We have confirmed the previous assignment of the ACPP gene to chromosome 3 by probing a panel of 25 human-Chinese hamster somatic cell hybrids, and we have further localized the ACPP gene to chromosome 3q21-q23 by fluorescence in situ hybridization.
Authors:
S S Li; F S Sharief
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Genomics     Volume:  17     ISSN:  0888-7543     ISO Abbreviation:  Genomics     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-12-29     Completed Date:  1993-12-29     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  765-6     Citation Subset:  IM    
Affiliation:
Laboratory of Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709.
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MeSH Terms
Descriptor/Qualifier:
Acid Phosphatase / genetics*
Animals
Chromosome Banding
Chromosome Mapping
Chromosomes, Human, Pair 3*
Cricetinae
DNA, Complementary / genetics
Genetic Markers
Humans
Hybrid Cells
In Situ Hybridization, Fluorescence
Male
Prostate / enzymology*
Prostatic Neoplasms / enzymology,  genetics
Chemical
Reg. No./Substance:
0/DNA, Complementary; 0/Genetic Markers; EC 3.1.3.2/Acid Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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