Document Detail


A prospective trial of a new self-expanding plastic stent for malignant esophageal obstruction.
MedLine Citation:
PMID:  11374667     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: We studied a new expandable plastic stent in the palliation of malignant esophageal obstruction. METHODS: Eight patients with malignant esophageal obstruction and dysphagia were studied. An expandable covered plastic stent made of polyester netting and covered with a silicone membrane was inserted and released into the stenosis. Relief of dysphagia and functional status were measured. RESULTS: The stent was successfully inserted in all eight patients. The median dysphagia score dropped from 3 (able to eat liquids only) to 1 (some dysphagia with solid food), and seven of the eight patients had an improvement of at least two grades of dysphagia. Mean survival was 87 days (range 17-226). Stent migration occurred in one patient after 50 days; stent occlusion due to tumor ingrowth was not seen. CONCLUSIONS: A low cost (approximately $400) expandable plastic stent has been developed that is safe and effective in the palliation of malignant esophageal obstruction. Large randomized trials comparing this stent to expandable metal stents are warranted.
Authors:
N Bethge; N Vakil
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  96     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-25     Completed Date:  2001-06-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1350-4     Citation Subset:  IM    
Affiliation:
Krankenhaus Neukölln, Berlin, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Constriction, Pathologic
Deglutition Disorders / etiology
Equipment Design
Esophageal Diseases / complications,  etiology*,  radiography,  therapy*
Esophageal Neoplasms / complications*
Esophagoscopy
Female
Foreign-Body Migration / etiology
Humans
Male
Plastics
Prospective Studies
Stents* / adverse effects
Survival Analysis
Chemical
Reg. No./Substance:
0/Plastics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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