Document Detail

A prospective trial of a new self-expanding plastic stent for malignant esophageal obstruction.
MedLine Citation:
PMID:  11374667     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: We studied a new expandable plastic stent in the palliation of malignant esophageal obstruction. METHODS: Eight patients with malignant esophageal obstruction and dysphagia were studied. An expandable covered plastic stent made of polyester netting and covered with a silicone membrane was inserted and released into the stenosis. Relief of dysphagia and functional status were measured. RESULTS: The stent was successfully inserted in all eight patients. The median dysphagia score dropped from 3 (able to eat liquids only) to 1 (some dysphagia with solid food), and seven of the eight patients had an improvement of at least two grades of dysphagia. Mean survival was 87 days (range 17-226). Stent migration occurred in one patient after 50 days; stent occlusion due to tumor ingrowth was not seen. CONCLUSIONS: A low cost (approximately $400) expandable plastic stent has been developed that is safe and effective in the palliation of malignant esophageal obstruction. Large randomized trials comparing this stent to expandable metal stents are warranted.
N Bethge; N Vakil
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  96     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-25     Completed Date:  2001-06-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1350-4     Citation Subset:  IM    
Krankenhaus Neukölln, Berlin, Germany.
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MeSH Terms
Constriction, Pathologic
Deglutition Disorders / etiology
Equipment Design
Esophageal Diseases / complications,  etiology*,  radiography,  therapy*
Esophageal Neoplasms / complications*
Foreign-Body Migration / etiology
Prospective Studies
Stents* / adverse effects
Survival Analysis
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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