Document Detail

A prospective study on the use of a non-adhesive gelling foam dressing on exuding leg ulcers.
MedLine Citation:
PMID:  17722523     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This non-comparative phase II study aimed to evaluate the safety and performance of a non-adhesive gelling foam dressing (GFD-N) in leg ulcer management. METHOD: Forty-six subjects with moderately to heavily exuding leg ulcers were treated with a regimen including GFD-N. Dressings were changed at least every seven days for four weeks or until healing. RESULTS: Mean GFD-N wear time was 3.2 days per subject. Mean wound area decreased from 10.1 cm2 at baseline to 5.1 cm2 at four weeks (p<0.001) and healed in five subjects (11%). The surrounding skin improved or remained stable in all but one subject. When compared with pre-study dressings, ulcer pain decreased for GFD-N, both with the dressing in place (p<0.001) and on dressing removal (p<0.001). Of final investigator ratings for 45 subjects, most were 'excellent' for ease of application (89%), ease of removal (96%), conformability (67%) and overall performance (58%). Five subjects experienced adverse events; none were serious or dressing-related. CONCLUSION: This small study demonstrates that GFD-N was safe, effective and convenient for wound healing, exudate management, pain/comfort and ease of use.
W Vanscheidt; K C Münter; W Klövekorn; F Vin; J-P Gauthier; A Ukat
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Publication Detail:
Type:  Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of wound care     Volume:  16     ISSN:  0969-0700     ISO Abbreviation:  J Wound Care     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-08-28     Completed Date:  2007-11-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9417080     Medline TA:  J Wound Care     Country:  England    
Other Details:
Languages:  eng     Pagination:  261-5     Citation Subset:  N    
Dermatologische Gemeinschaftspraxis, University Freiburg, Germany.
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MeSH Terms
Exudates and Transudates
Leg Ulcer / physiopathology,  therapy*
Prospective Studies
Wound Healing
Reg. No./Substance:

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