Document Detail


A prospective study comparing intravenous tenoxicam with rectal diclofenac for pain relief in day case surgery.
MedLine Citation:
PMID:  9785068     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a prospective, randomized, double-blind study, we compared intravenous tenoxicam with rectal diclofenac for post-operative pain relief after day case arthroscopy or laparoscopic sterilization. Intravenous tenoxicam (40 mg) was administered as a single bolus at induction, or rectal diclofenac (100 mg) was administered immediately after induction. Both groups were similar with respect to age, weight, sex of the patients, the operation performed and the operative time. There were no significant differences observed between the groups for pain scores at 30 min, 60 min and 24 h post-operatively. The time to first analgesic requirement, the dose of pethidine administered and total analgesic requirements in the first 24 h post-operatively were equivalent in both groups. In view of the similar efficacy of both of these drugs, patient preference and ease of administration, the use of tenoxicam is appropriate in many patients undergoing day case surgery.
Authors:
S A Colbert; C McCrory; D M O'Hanlon; M Scully; A Tanner; M Doyle
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  15     ISSN:  0265-0215     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-12-17     Completed Date:  1998-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  544-8     Citation Subset:  IM    
Affiliation:
National Children's Hospital, Dublin, Ireland.
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MeSH Terms
Descriptor/Qualifier:
Administration, Rectal
Adult
Aged
Ambulatory Surgical Procedures*
Analgesics, Opioid / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / administration & dosage,  therapeutic use*
Arthroscopy
Diclofenac / administration & dosage,  therapeutic use*
Double-Blind Method
Endoscopy
Female
Humans
Injections, Intravenous
Laparoscopy
Male
Meperidine / therapeutic use
Middle Aged
Pain, Postoperative / prevention & control*
Piroxicam / administration & dosage,  analogs & derivatives*,  therapeutic use
Premedication
Prospective Studies
Sterilization, Reproductive
Time Factors
Chemical
Reg. No./Substance:
0/Analgesics, Opioid; 0/Anti-Inflammatory Agents, Non-Steroidal; 15307-86-5/Diclofenac; 36322-90-4/Piroxicam; 57-42-1/Meperidine; 59804-37-4/tenoxicam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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