Document Detail


A prospective randomized trial of intravenous magnesium versus intravenous propranolol in acute myocardial infarction.
MedLine Citation:
PMID:  7786689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A total of 266 patients entered into a study comparing the effect of intravenous magnesium and propranolol following acute myocardial infarction. Of these, 97 were able to receive either drug and were therefore randomized into the magnesium (n = 51) or propranolol group (n = 46). 88 patients were unable to receive propranolol and formed a third group (NR) while a further 81 patients could not receive either drug and formed a fourth group (N). The study showed that intravenous magnesium was as effective in preventing potentially lethal arrhythmias as propranolol and could be given to some 70 per cent of such patients whereas propranolol could only be given to 36 per cent.
Authors:
J Balkin; D Rosenmann; M Ilan; M Klutstein; M M Zion; A S Abraham
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Magnesium research : official organ of the International Society for the Development of Research on Magnesium     Volume:  7     ISSN:  0953-1424     ISO Abbreviation:  Magnes Res     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-07-24     Completed Date:  1995-07-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8900948     Medline TA:  Magnes Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  267-71     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel.
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Heart Block / epidemiology,  etiology
Humans
Incidence
Infusions, Intravenous
Injections, Intravenous
Magnesium Sulfate / administration & dosage,  therapeutic use*
Male
Middle Aged
Myocardial Infarction / complications,  drug therapy*,  mortality
Propranolol / administration & dosage,  therapeutic use*
Prospective Studies
Pulmonary Edema / epidemiology,  etiology
Shock, Cardiogenic / epidemiology,  etiology
Treatment Outcome
Ventricular Fibrillation / epidemiology,  etiology,  prevention & control
Chemical
Reg. No./Substance:
525-66-6/Propranolol; 7487-88-9/Magnesium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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