Document Detail


A prospective multicenter study to evaluate the feasibility and safety of aggressive antihypertensive treatment in patients with acute intracerebral hemorrhage.
MedLine Citation:
PMID:  15665258     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors performed a multicenter prospective observational study to evaluate the feasibility and safety of intravenous antihypertensive protocol for acute hypertension in patients with intracerebral hemorrhage (ICH). Twenty-seven patients with ICH and acute hypertension (mean age 61.37 +/- 14.27; 10 were men) were treated to maintain the systolic blood pressure (BP) below 160 mm Hg and diastolic BP below 90 mm Hg within 24 hours of symptom onset. Neurological deterioration (defined as a decrease in initial Glasgow Coma Scale score > or = 2) was observed in 2 (7.4%) of 27 patients during treatment. Among patients who underwent follow-up computed tomography, hematoma expansion (more than 33% increase in hematoma size at 24 hours) was observed in 2 (9.1%) of 22 patients. Patients treated within 6 hours of symptom onset were more likely to be functionally independent (modified Rankin scale < or = 2) at 1 month compared with patients who were treated between 6 and 24 hours (8 of 18 versus 0 of 9,P = .03). Aggressive pharmacological treatment of acute hypertension in patients with ICH can be initiated early with a low rate of neurological deterioration and hematoma expansion.
Authors:
Adnan I Qureshi; Yousef M Mohammad; Abutaher M Yahia; Jose I Suarez; Amir M Siddiqui; Jawad F Kirmani; M Fareed K Suri; James Kolb; Osama O Zaidat
Related Documents :
7489688 - Prognostic significance of central motor conduction on the non-hemiplegic side in supra...
23999948 - Biomechanical evaluation of different suture materials for arthroscopic transtibial pul...
10853118 - Gamma knife radiosurgery for trigeminal neuralgia: experience at the barrow neurologica...
22978688 - Low recurrence rate in treating atrioventricular nodal reentrant tachycardia with tripl...
19524938 - Topical heparin: a promising agent for the prevention of tracheal stenosis in airway su...
10939778 - The economic evaluation of complementary medicine: a staged approach at the royal londo...
Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study    
Journal Detail:
Title:  Journal of intensive care medicine     Volume:  20     ISSN:  0885-0666     ISO Abbreviation:  J Intensive Care Med     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2005-01-24     Completed Date:  2005-04-14     Revised Date:  2006-10-13    
Medline Journal Info:
Nlm Unique ID:  8610344     Medline TA:  J Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-42     Citation Subset:  IM    
Affiliation:
Zennat Qureshi Stroke Research Center, Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103-2425, USA. aiqureshi@hotmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acute Disease
Algorithms
Analysis of Variance
Antihypertensive Agents / therapeutic use*
Cerebral Hemorrhage / complications,  drug therapy*,  radiography
Cerebrovascular Circulation / drug effects
Feasibility Studies
Female
Humans
Hypertension / drug therapy*,  etiology
Male
Middle Aged
Prospective Studies
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  CVP and PAoP measurements are discordant during fluid therapy after traumatic brain injury.
Next Document:  Acute effects of upright position on gas exchange in patients with acute respiratory distress syndro...