| A prospective multicenter randomized trial of tension-free vaginal tape and colposuspension for primary urodynamic stress incontinence: two-year follow-up. | |
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MedLine Citation:
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PMID: 14981369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: This study was undertaken to compare tension-free vaginal tape (TVT) with colposuspension as the primary treatment for stress incontinence. STUDY DESIGN: The trial was conducted in gynecology or urology departments in 14 centers in the United Kingdom and Ireland. Three hundred forty-four women with urodynamic stress incontinence were randomly assigned to groups: 175 to TVT and 169 to colposuspension. Patients were assessed using the Short Form-36 health status questionnaire, the Bristol Female Lower Urinary Tract Symptoms questionnaire, clinical examination, and a 1-hour perineal pad test. Unpaired and paired data were analyzed with the Wilcoxon rank sum and matched pairs tests, respectively, and proportions were compared with the Fisher exact test. RESULTS: When data were analyzed on an intention-to-treat basis, assuming patients with missing data to be treatment failures, 63% of the TVT group and 51% of the colposuspension group were objectively cured at 2 years (odds ratio 1.67, 95% CI 1.09-2.58). CONCLUSION: The TVT procedure appears to be as effective as colposuspension for the treatment of urodynamic stress incontinence at 2 years. |
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Authors:
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Karen L Ward; Paul Hilton; |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 190 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-02-24 Completed Date: 2004-03-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 324-31 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynaecology, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Follow-Up Studies Health Status Indicators Humans Life Style Postoperative Complications Prolapse Prospective Studies Prostheses and Implants* Urinary Bladder / surgery* Urinary Bladder Diseases / surgery Urinary Incontinence, Stress / surgery, therapy* Urodynamics |
| Comments/Corrections | |
Comment In:
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Am J Obstet Gynecol. 2005 Mar;192(3):984-5; author reply 985
[PMID:
15746704
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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