Document Detail

A prospective multicenter randomized trial of tension-free vaginal tape and colposuspension for primary urodynamic stress incontinence: two-year follow-up.
MedLine Citation:
PMID:  14981369     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study was undertaken to compare tension-free vaginal tape (TVT) with colposuspension as the primary treatment for stress incontinence. STUDY DESIGN: The trial was conducted in gynecology or urology departments in 14 centers in the United Kingdom and Ireland. Three hundred forty-four women with urodynamic stress incontinence were randomly assigned to groups: 175 to TVT and 169 to colposuspension. Patients were assessed using the Short Form-36 health status questionnaire, the Bristol Female Lower Urinary Tract Symptoms questionnaire, clinical examination, and a 1-hour perineal pad test. Unpaired and paired data were analyzed with the Wilcoxon rank sum and matched pairs tests, respectively, and proportions were compared with the Fisher exact test. RESULTS: When data were analyzed on an intention-to-treat basis, assuming patients with missing data to be treatment failures, 63% of the TVT group and 51% of the colposuspension group were objectively cured at 2 years (odds ratio 1.67, 95% CI 1.09-2.58). CONCLUSION: The TVT procedure appears to be as effective as colposuspension for the treatment of urodynamic stress incontinence at 2 years.
Karen L Ward; Paul Hilton;
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  190     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-24     Completed Date:  2004-03-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  324-31     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynaecology, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom.
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MeSH Terms
Follow-Up Studies
Health Status Indicators
Life Style
Postoperative Complications
Prospective Studies
Prostheses and Implants*
Urinary Bladder / surgery*
Urinary Bladder Diseases / surgery
Urinary Incontinence, Stress / surgery,  therapy*
Comment In:
Am J Obstet Gynecol. 2005 Mar;192(3):984-5; author reply 985   [PMID:  15746704 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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