Document Detail


A prospective longitudinal study on rotation thromboelastometry in women with uncomplicated pregnancies and postpartum.
MedLine Citation:
PMID:  23278445     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Rotation thromboelastometry (ROTEM) is an easy, fast and complete method of measuring coagulation. AIMS: Our goal was to obtain longitudinal values on ROTEM in uncomplicated pregnancies and in the puerperium. MATERIALS AND METHODS: Healthy women, who visited our outpatient clinic for antenatal checks and who accomplished an uncomplicated pregnancy were tested three times during pregnancy and one time postpartum. Intrinsic and extrinsic pathway tests were carried out. RESULTS: In total, 62 women were analysed, and 298 measurements were taken. With increasing gestational age, there are significant changes towards hypercoagulability. CONCLUSION: This study provides a better knowledge about physiological changes in ROTEM measurements during pregnancy. These normative data may serve as assistance for future studies and interventions.
Authors:
Leonie E van Rheenen-Flach; Sonja Zweegman; Fleur Boersma; Joris E Lenglet; Jos W R Twisk; Antoinette C Bolte
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-31
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  -     ISSN:  1479-828X     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-1-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors ANZJOG © 2012 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.
Affiliation:
Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands.
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