| A prospective longitudinal evaluation of the benefits of epicardial lead placement for cardiac resynchronization therapy. | |
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MedLine Citation:
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PMID: 19797148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: Cardiac resynchronization therapy (CRT) is a recognized treatment for appropriate patients. However, placement of the transvenous left ventricular lead is unsuccessful in 5-10% of patients and a further 20% fail to respond. For these groups, epicardial left ventricular lead placement is one alternative. We prospectively evaluated the effects of epicardial vs. transvenous placed CRT. METHODS AND RESULTS: Twenty-three subjects with unsuccessful transvenous coronary sinus lead placement underwent epicardial implantation. The subjects underwent clinical evaluation, cardiopulmonary exercise testing, and echocardiography before 3 and 6 months after. The results were compared with a control group (n = 35) who had received transvenous CRT. In both groups, there were significant improvements in all measures at 3 and 6 months. The improvement in peak VO(2) was delayed in the epicardial group compared with the transvenous group. At 6 months, the improvements seen in all variables showed no difference between the groups. CONCLUSION: Epicardial lead placement is a viable option for patients with unsuccessful coronary sinus lead placement. The improvements in most variables were of a similar magnitude and over a similar time scale compared with transvenous placement. Improvements in peak VO(2) were delayed in the epicardial group, probably as a result of a prolonged recovery time. |
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Authors:
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Ashish Patwala; Paul Woods; Richard Clements; Khaled Albouaini; Archana Rao; David Goldspink; Lip-Bun Tan; Aung Oo; David Wright |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Volume: 11 ISSN: 1532-2092 ISO Abbreviation: Europace Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-02 Completed Date: 2010-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883649 Medline TA: Europace Country: England |
Other Details:
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Languages: eng Pagination: 1323-9 Citation Subset: IM |
Affiliation:
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Liverpool Heart and Chest Hospital, Liverpool L14 3PE, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cardiac Pacing, Artificial / methods* Electrodes, Implanted* Female Heart Failure / diagnosis, prevention & control* Heart Ventricles / surgery* Humans Longitudinal Studies Male Pacemaker, Artificial* Pericardium / surgery* Prospective Studies Prosthesis Implantation / methods* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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