Document Detail


A prospective critical evaluation of in vitro thyroid function tests.
MedLine Citation:
PMID:  3766208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A number of 2 325 serum samples from a population of in- and outpatients were collected during a six-month period in order to evaluate the usefulness of various thyroid function tests in the clinical laboratory routine. The samples were analysed with the following thyroid function tests: total triiodothyronine (T3) (TT3), total thyroxine (T4) (TT4), free T3 index (FT3I), free T4 index (FT4I) and thyrotropin (TSH). One to two years after the primary evaluation, a follow-up was performed and the final diagnoses were checked in the patients' records. The values of these parameters in the diagnosis of hyperthyroidism were: FT3I greater than FT4I greater than TT3 greater than TT4. The corresponding results in the diagnosis of hypothyroidism were: TSH greater than FT4I greater than FT3I = TT3. No single test could detect both hyper- and hypothyroidism effectively. The only one-step strategy for thyroid evaluation in patients without apparent clinical signs of hyper- or hypothyroidism would therefore be the combined determination of T3 and TSH. The study also showed distinct differences between the reference values of the healthy population and patients without thyroid disorders.
Authors:
U B Ericsson; J I Thorell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  220     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1986  
Date Detail:
Created Date:  1986-11-10     Completed Date:  1986-11-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  47-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Evaluation Studies as Topic
Female
Follow-Up Studies
Humans
Hyperthyroidism / diagnosis
Hypothyroidism / diagnosis
Male
Middle Aged
Prospective Studies
Thyroid Function Tests / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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