Document Detail


A prospective clinical and bacteriologic study of inguinal buboes in Thai men.
MedLine Citation:
PMID:  8838178     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One-hundred thirteen men (mean age, 23 years) who presented with inguinal buboes to a government-operated hospital for sexually transmitted diseases (STDs) in Bangkok were studied between February 1987 and February 1989. The median duration of preceding symptoms was 7 days (range, 1-62 days). The majority of patients (74; 65%) had received treatment previously; 31 (27%) were febrile, 13 (12%) had extrainguinal lymphadenopathy, and 31 (27%) had concurrent active genital ulcers. There was no history of genital ulceration in 66 (58%) of the patients. Pus was obtained from 51 of the 110 buboes aspirated for culture; 21 (41%) of these cultures yielded Haemophilus ducreyi, and 2 (3.9%) were positive for Chlamydia trachomatis on immunofluorescence microscopy. Saline (1 mL) was injected and reaspirated from the buboes of 35 of the other 59 patients; 3 buboes yielded H. ducreyi and 9 were positive for C. trachomatis. All cultures for other aerobic and anaerobic bacteria and viruses in intact buboes were negative. Syphilis serology was positive in only one case. Patients attending STD clinics in this region who have large, fluctuant, edematous inguinal buboes containing pus should receive presumptive treatment for chancroid. If there is no pus, then the bubo is more likely to be caused by lymphogranuloma venereum.
Authors:
C Viravan; D A Dance; C Ariyarit; S Looareesuwan; Y Wattanagoon; T M Davis; V Wuthiekanun; S Tantivanich; B J Angus; N J White
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  22     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-12-03     Completed Date:  1996-12-03     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  233-9     Citation Subset:  IM    
Affiliation:
Bangkok Hospital for Tropical Diseases, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anti-Bacterial Agents / therapeutic use
Chancroid / drug therapy,  microbiology*,  physiopathology
Chlamydia trachomatis / isolation & purification*
Erythromycin / therapeutic use
Haemophilus ducreyi / isolation & purification*
Humans
Lymph Nodes / microbiology
Lymphogranuloma Venereum / drug therapy,  microbiology*,  physiopathology
Male
Prospective Studies
Tetracycline / therapeutic use
Thailand
Grant Support
ID/Acronym/Agency:
//Wellcome Trust
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 114-07-8/Erythromycin; 60-54-8/Tetracycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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