Document Detail

A prospective blinded evaluation of exercise thallium-201 SPET in patients with suspected chronic exertional compartment syndrome of the leg.
MedLine Citation:
PMID:  11440028     Owner:  NLM     Status:  MEDLINE    
This study compared the quantitative and qualitative results of leg thallium-201 single-photon emission tomography (SPET) imaging in patients with and without raised intracompartmental pressure associated with exercise-related leg pain. The purpose of this study was to clarify the aetiology of chronic exertional compartment syndrome (CECS), and to investigate the diagnostic applications of 201Tl SPET in CECS. Thirty-four study participants underwent compartment pressure testing (CPT) between March and August 2000. There were 25 positive CPT results (patient group), and nine negative CPT results (control group). All 34 participants underwent scintigraphy. Quantitative and qualitative assessments were performed for the anterolateral and deep posterior compartments of the lower leg. There was no significant difference in either quantitative or qualitative assessments of perfusion between those compartments with and those without CECS. In contrast, a marked effect of exercise type upon compartment perfusion pattern was noted. Results of this study indicate that there is no compartment perfusion deficit in those patients with raised intracompartmental pressure associated with CECS, and suggest a non-ischaemic basis for the pain associated with CECS. They also suggest no role for exercise perfusion scintigraphy in the diagnosis of this syndrome.
L Trease; B van Every; K Bennell; P Brukner; J Rynderman; A Baldey; A Turlakow; M J Kelly
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  28     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-07-06     Completed Date:  2001-12-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  688-95     Citation Subset:  IM    
Nuclear Medicine Department, The Alfred Hospital, Victoria, Australia.
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MeSH Terms
Blood Pressure / physiology
Chronic Disease
Compartment Syndromes / radionuclide imaging*
Exercise / physiology*
Image Processing, Computer-Assisted
Ischemia / radionuclide imaging
Leg / blood supply
Prospective Studies
Regional Blood Flow / physiology
Thallium / diagnostic use
Tomography, Emission-Computed, Single-Photon
Reg. No./Substance:

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