Document Detail

A prospective assessment of breath-hold fast spin echo and inversion recovery fast spin echo techniques for detection and characterization of focal hepatic lesions.
MedLine Citation:
PMID:  10913716     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to prospectively assess two breath-hold T(2)-weighted fast spin-echo sequences and two breath-hold inversion recovery fast spin-echo sequences to determine their relative ability to detect and characterize focal hepatic lesions. Fourteen patients with a total of nineteen proven focal hepatic lesions were imaged with two breath-hold T(2)-weighted (T2W) fast spin echo sequences (HASTE TE = 66 and HASTE TE = 120), two breath-hold inversion recovery fast spin echo sequences (IRFSE TE = 64 and IRFSE TE = 95), and a nonbreath-hold T(2)-weighted fast-spin echo sequence (FSE TE = 96-120). Contrast-to-noise ratios (CNRs) were measured for all proven lesions on all sequences. Both IRFSE sequences and the HASTE sequence with TE = 66 showed an improvement in lesion-liver and liver-spleen CNRs compared to the nonbreath-hold T2W sequence. The mean difference in CNR between benign and malignant lesions was largest for the HASTE TE = 120 sequence. These preliminary results suggest that a breath-hold IRFSE sequence (TE = 64 or 95) has an equal ability to detect focal hepatic lesions as a nonbreath-hold T2W FSE sequence (TE = 96-120). The HASTE TE = 120 showed the greatest ability to discriminate between benign and malignant lesions.
R S Pawluk; J A Borrello; J J Brown; E G McFarland; S A Mirowitz; L Y Tsao
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Magnetic resonance imaging     Volume:  18     ISSN:  0730-725X     ISO Abbreviation:  Magn Reson Imaging     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-10-12     Completed Date:  2000-10-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8214883     Medline TA:  Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  543-51     Citation Subset:  IM    
Mallinckrodt Institute of Radiology, Washington University Medical Center, St. Louis, MO 63110, USA.
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MeSH Terms
Liver Neoplasms / diagnosis*,  pathology
Magnetic Resonance Imaging / methods*
Middle Aged
Spin Labels
Spleen / pathology
Reg. No./Substance:
0/Spin Labels

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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