Document Detail

A proposal for the timing of management of patients with melanoma presenting during pregnancy.
MedLine Citation:
PMID:  22331751     Owner:  NLM     Status:  MEDLINE    
The treatment of melanoma during and immediately after pregnancy poses a significant challenge to surgeons, oncologists, and patients alike. With the overall increase in incidence of melanoma in the United States and worldwide, it is likely that more surgeons will be faced with management decisions regarding pregnant patients with melanoma. We report on five patients who presented to the Yale Melanoma Unit with melanoma during their pregnancy. We propose the management option of resection of the primary tumor under local anesthesia, and postponing of the sentinel lymph node biopsy until after the birth of the child. The completion lymphadenectomy can be performed if these nodes are found to be harboring metastases. We further discuss treatment options and propose an algorithm for management of patients diagnosed with melanoma while pregnant.
Niclas Broer; Samuel Buonocore; Carolyn Goldberg; Carolyn Truini; Marc B Faries; Deepak Narayan; Stephan Ariyan
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural     Date:  2012-02-13
Journal Detail:
Title:  Journal of surgical oncology     Volume:  106     ISSN:  1096-9098     ISO Abbreviation:  J Surg Oncol     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-06-07     Completed Date:  2012-08-06     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  0222643     Medline TA:  J Surg Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  36-40     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Section of Plastic Surgery, Department of Surgery, Yale School of Medicine, Yale Melanoma Unit at the Yale Cancer Center, New Haven, CT, USA.
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MeSH Terms
Decision Trees
Lymph Node Excision
Lymph Nodes / pathology,  surgery
Lymphatic Metastasis
Melanoma / diagnosis*,  pathology,  surgery*
Neoplasm Staging
Pregnancy Complications, Neoplastic / diagnosis*,  pathology,  surgery*
Pregnancy Trimesters
Retrospective Studies
Sentinel Lymph Node Biopsy*
Skin Neoplasms / diagnosis*,  pathology,  surgery*
Treatment Outcome
Grant Support
1 P50 CA121974/CA/NCI NIH HHS; CA-16359/CA/NCI NIH HHS; P50 CA121974/CA/NCI NIH HHS; P50 CA121974-05/CA/NCI NIH HHS
Comment In:
J Surg Oncol. 2012 Dec;106(8):1008   [PMID:  22674350 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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