| prophylactic-intragraft-injection-nicardipine-prior-saphenous-vein-graft-percutaneous-inter. | |
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MedLine Citation:
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PMID: 21562350 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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No-reflow is a failure to restore normal coronary flow despite appropriate treatment of coronary obstruction. It is most commonly seen during interventions in saphenous vein grafts and is associated with poor outcome. The cause of no-reflow is complex and multifactorial. Various mechanisms including vasospasm and distal embolization of debris released during the intervention have been explained as the cause of no-reflow. Treatment to prevent or reverse no-reflow includes, but is not limited to, protective devices and intracoronary vasodilators. Intracoronary nicardipine seems to be the best option in preventing no-reflow regarding its minimal systemic side effects, modest negative inotropic and chronotropic effects, duration of action and feasibility of use. The goal of this manuscript is to review the effects of prophylactic intragraft nicardipine injection for prevention of no-reflow during saphenous vein graft intervention. |
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Authors:
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Mohammad Reza Habibzadeh; Hoang Thai; Mohammad Reza Movahed |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of invasive cardiology Volume: 23 ISSN: 1557-2501 ISO Abbreviation: J Invasive Cardiol Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8917477 Medline TA: J Invasive Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 202-6 Citation Subset: IM |
Affiliation:
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The Southern Arizona VA Health Care System and University of Arizona Sarver Heart Center, 1501 North Campbell Avenue, Tucson, AZ 85724 USA. rmova@aol.com. |
Export Citation:
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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