| The prolamin antibody reactivity against hordein polypeptides in sera from patients with coeliac disease. | |
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MedLine Citation:
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PMID: 3180476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The antibody reactivity against the barley prolamin, hordein, was investigated by an immunoblotting technique, in sera from patients with untreated coeliac disease, patients with other gastrointestinal diseases and healthy controls. No characteristic hordein polypeptide antibody pattern could be connected to coeliac disease, as observed in a similar study using different fractions of the wheat prolamin, gliadin. Gliadin- and hordein-immunoadsorbent column experiments demonstrated that the prolamin reactivity originates from the same population of antibodies. It is speculated that distinct antigenic epitopes characteristic for untreated coeliac disease, might reside within a N-terminal repeat region of gliadin. |
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Authors:
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S U Friis; H Sjöström; O Norén; N Rüdiger; D Anthonsen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinica chimica acta; international journal of clinical chemistry Volume: 176 ISSN: 0009-8981 ISO Abbreviation: Clin. Chim. Acta Publication Date: 1988 Sep |
Date Detail:
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Created Date: 1988-12-22 Completed Date: 1988-12-22 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 1302422 Medline TA: Clin Chim Acta Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 241-50 Citation Subset: IM |
Affiliation:
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Medical Department P, Rigshospitalet, Copenhagen, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies / immunology* Blotting, Western Celiac Disease / blood* Glutens Humans Plant Proteins / blood, immunology* Prolamins Proteins / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 0/Plant Proteins; 0/Prolamins; 0/Proteins; 8002-80-0/Glutens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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