Document Detail

The progression of nonsegmental vitiligo: clinical analysis of 318 patients.
MedLine Citation:
PMID:  9466196     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Vitiligo is an acquired disorder with destruction of melanocytes and is characterized by cutaneous depigmentation with a progressive clinical course. We attempted to evaluate whether there was a relationship between the initial site and ultimate progression of nonsegmental vitiligo. METHODS: Three hundred and eighteen nonsegmental vitiligo patients were examined. Questionnaires regarding age, sex, duration of disease, family history, distribution of initial lesions, progression, and clinical type were recorded from personal interviews and case notes. RESULTS: Two hundred and eighty nine (90.9%) of the 318 patients showed progression of vitiligo at the time of examination. When the initial sites were the posterior trunk, hands, or feet, there was more progression of vitiligo to other body areas. The progression pattern was usually contiguous to the initial site. When the hands were the initial site, however, vitiligo most commonly progressed to the face. CONCLUSIONS: There may be a possible relationship between the initial site and ultimate progression of nonsegmental vitiligo. The progression pattern is usually contiguous to the initial site.
W H Chun; S K Hann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  36     ISSN:  0011-9059     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-03-30     Completed Date:  1998-03-30     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  908-10     Citation Subset:  IM    
Department of Dermatology, Yonsei University College of Medicine, Seoul, South Korea.
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MeSH Terms
Back / pathology
Disease Progression
Facial Dermatoses / pathology
Foot Dermatoses / pathology
Hand Dermatoses / pathology
Korea / epidemiology
Neck / pathology
Skin Diseases / pathology
Vitiligo / epidemiology*

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