Document Detail

The progress of mitral regurgitation after isolated coronary artery bypass in cases of ischemic mitral regurgitation.
MedLine Citation:
PMID:  16431404     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Mitral valve intervention combined with coronary artery bypass surgery is inevitable in the case of severe mitral regurgitation in patients with coronary artery disease because the prognosis is poor without mitral correction. The best treatment protocol for patients with a moderate degree of mitral regurgitation is under debate. To clarify the optimal management for these patients, we evaluated the progress of mitral regurgitation after isolated coronary artery bypass surgery in cases of ischemic mitral regurgitation. METHODS; The study was conducted between March 2001 and April 2003. Forty-seven patients (70% men, with a mean age of 61 years, a mean ejection fraction of 43.7%, and a mean New York Heart Association class of 2.53) with preoperative diagnoses of moderate degree ischemic mitral regurgitation (Grade 3 mitral regurgitation on a scale of 0 to 4) and coronary artery disease, without leaflet pathology, underwent isolated coronary artery bypass surgery. Patients were followed-up at a mean of 22 months and an echocardiographic evaluation was done to determine the progress of the mitral disease. RESULTS: The 30-day operative mortality rate was 2.1%. In the postoperative period, the mean ejection fraction was 46.9% and the mean functional capacity of the patients was 1.31. Mitral regurgitation regressed to a mild degree in 56.9% of the patients. The 2-year survival rate was 93.7%. CONCLUSIONS: Patients with moderate ischemic mitral regurgitation and coronary artery disease who underwent coronary artery bypass surgery alone had acceptable results. We are of the opinion that isolated coronary artery bypass surgery might be a good treatment choice for moderate degree ischemic mitral regurgitation.
Ali Gürbüz; Banu Lafci; Sahin Bozok; Levent Yilik; Ibrahim Ozsöyler; Orhan Gökalp; Nagihan Karahan; Cengiz Ozbek
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The heart surgery forum     Volume:  9     ISSN:  1522-6662     ISO Abbreviation:  Heart Surg Forum     Publication Date:  2006  
Date Detail:
Created Date:  2006-01-24     Completed Date:  2006-12-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100891112     Medline TA:  Heart Surg Forum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E555-9     Citation Subset:  IM    
Department of Cardiovascular Surgery, Atatürk Education and Research Hospital, Izmir, Turkey.
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MeSH Terms
Coronary Artery Bypass / methods*
Coronary Artery Disease / complications*,  surgery*
Disease Progression
Middle Aged
Mitral Valve Insufficiency / complications*,  surgery*
Myocardial Ischemia / complications*,  surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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