Document Detail

A program for treating olanzapine-related weight gain.
MedLine Citation:
PMID:  11433117     Owner:  NLM     Status:  MEDLINE    
This study evaluated the effectiveness of a Weight Watchers program for patients with schizophrenia who had olanzapine-related weight gain and ascertained whether the severity of patients' psychiatric symptoms was correlated with the patients' success in losing weight. Seven men and four women who had been treated with olanzapine and who had gained at least 7 percent of their pretreatment body weight attended Weight Watchers meetings and were offered supervised exercise sessions. The patients' weight, body mass index, and psychiatric symptoms were assessed and were compared with those of a matched comparison group who did not attend the Weight Watchers program. Only the men experienced significant weight loss. No correlation was found between weight loss and exercise or change in psychiatric symptoms.
M P Ball; V B Coons; R W Buchanan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Psychiatric services (Washington, D.C.)     Volume:  52     ISSN:  1075-2730     ISO Abbreviation:  Psychiatr Serv     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-02     Completed Date:  2001-08-30     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9502838     Medline TA:  Psychiatr Serv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  967-9     Citation Subset:  IM    
Maryland Psychiatric Research Center at the University of Maryland School of Medicine, Baltimore 21228, USA.
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MeSH Terms
Analysis of Variance
Antipsychotic Agents / adverse effects*
Case-Control Studies
Diet, Reducing*
Middle Aged
Pirenzepine / adverse effects*,  analogs & derivatives
Program Evaluation
Schizophrenia / drug therapy
Severity of Illness Index
Sex Factors
Weight Gain / drug effects*
Weight Loss*
Grant Support
Reg. No./Substance:
0/Antipsychotic Agents; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 28797-61-7/Pirenzepine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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