| The prognostic value of body mass index and standard exercise testing in male veterans with congestive heart failure. | |
| | |
MedLine Citation:
|
PMID: 12397568 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To evaluate the prognostic characteristics of body mass index (BMI) and standard exercise test variables in a consecutive series of patients with mild to moderate congestive heart failure (CHF) referred for standard exercise tests. BACKGROUND: Controversy exists regarding the prognostic importance of BMI, etiology, and exercise test variables in patients with CHF. METHODS: All patients referred for evaluation at two university-affiliated Veterans Affairs Medical Centers who underwent treadmill tests for clinical indications between 1987 and 2000 were determined to be dead or alive using the Social Security Death Index after a mean 6 years follow-up. Clinical and exercise test variables were collected prospectively according to standard definitions; testing and data management were performed in a standardized fashion using a computer-assisted protocol. Survival analysis was performed using all-cause mortality as the endpoint for follow-up. RESULTS: A total of 522 patients with a history and clinical findings of CHF underwent exercise testing. Forty-two percent died during the follow-up period, for an average annual mortality of 6.7%. Cox proportional hazards model chose peak metabolic equivalents (METs), BMI, age, and ischemic etiology in rank order as independently and significantly associated with time to death. A score based on these variables classified patients into low (2% annual mortality), medium (5.2%), and high-risk groups (7% annual mortality). CONCLUSION: Standard exercise testing and BMI can be used to estimate prognosis in outpatients with heart failure. A score incorporating METs, BMI, age, and etiology efficiently stratified these patients. BMI was chosen by the survival analysis, confirming its surprising inverse relationship to prognosis in CHF patients (i.e., heavier patients do better). |
| | |
Authors:
|
Lynette W Lissin; Andre J Gauri; Victor F Froelicher; Afshin Ghayoumi; Jonathan Myers; John Giacommini |
Related Documents
:
|
9572798 - Altered mechanisms of sympathetic activation during rhythmic forearm exercise in heart ... 15159038 - Brain natriuretic peptide kinetics during dynamic exercise in patients with chronic hea... 18514618 - Oral amino acid supplements improve exercise capacities in elderly patients with chroni... 8007798 - Exercise testing and training in patients with chronic heart failure. 16168168 - A community-based exercise programme for older persons with knee pain using telemedicine. 16764918 - Reproductive endocrine dysfunction in atlantic croaker exposed to hypoxia. |
Publication Detail:
|
Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
|
Title: Journal of cardiac failure Volume: 8 ISSN: 1071-9164 ISO Abbreviation: J. Card. Fail. Publication Date: 2002 Aug |
Date Detail:
|
Created Date: 2002-10-24 Completed Date: 2003-01-07 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9442138 Medline TA: J Card Fail Country: United States |
Other Details:
|
Languages: eng Pagination: 206-15 Citation Subset: IM |
Affiliation:
|
Division of Cardiovascular Medicine, Stanford University Medical Center, Palo Alto, California 94304, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aerospace Medicine Age Factors Aged Angina Pectoris / complications, epidemiology Body Mass Index* California Cardiomyopathies / classification, complications, epidemiology Exercise Test / standards* Follow-Up Studies Heart Failure / complications, diagnosis*, epidemiology Humans Male Middle Aged Military Personnel* Multivariate Analysis Prevalence Prognosis Proportional Hazards Models Risk Factors Survival Analysis Time Factors Veterans* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Association between progression of untreated coronary lesions and in-stent restenosis
Next Document: Low serum total cholesterol is associated with marked increase in mortality in advanced heart failur...