Document Detail


The prognostic importance of heart failure and age in patients treated with primary angioplasty.
MedLine Citation:
PMID:  12798826     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Effective risk stratification is essential in the management of patients with acute myocardial infarction. Available models have not yet been studied and validated in patients treated with primary angioplasty for acute myocardial infarction.
METHODS: The prognostic value of heart failure defined by Killip class and age upon admission and the impact of success and failure of the angioplasty procedure was studied in 1702 consecutive patients treated with primary angioplasty.
FINDINGS: The combination of Killip class and age is a strong predictor of 30-day mortality and categorizes patients in subgroups with 30-day mortality risk ranging from 0.5 to 70%. Angioplasty failure results in a high 30-day mortality, in particular in patients with Killip class > or =II and/or age > or =70 years. A large majority of patients (72%), characterized by Killip class I and age <70 years, can be identified with a 0.5% risk of death at 30 days.
INTERPRETATION: The presence of heart failure (Killip class) and age predicts 30-day mortality in patients on their way to the catheterization laboratory for primary angioplasty. This simple and effective early risk stratification, in combination with success and failure of the primary angioplasty, can be used to direct subsequent patient management.
Authors:
Jose P S Henriques; Felix Zijlstra; Menko-Jan de Boer; Arnoud W J van 't Hof; A T Marcel Gosselink; Jan-Henk E Dambrink; Harry Suryapranata; Jan C A Hoorntje
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of heart failure     Volume:  5     ISSN:  1388-9842     ISO Abbreviation:  Eur. J. Heart Fail.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-11     Completed Date:  2003-12-11     Revised Date:  2011-06-08    
Medline Journal Info:
Nlm Unique ID:  100887595     Medline TA:  Eur J Heart Fail     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  291-4     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Isala Klinieken, Locatie Weezenlanden, Groot Wezenland 20, 8011 JW Zwolle, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Aged
Aged, 80 and over
Angioplasty, Balloon, Coronary*
Electrocardiography
Female
Follow-Up Studies
Heart Failure / diagnosis*,  epidemiology,  therapy*
Humans
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction / diagnosis,  epidemiology,  therapy
Netherlands
Patient Admission
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors,  therapeutic use
Predictive Value of Tests
Prognosis
Risk Factors
Statistics as Topic
Survival Analysis
Time Factors
Treatment Outcome
Chemical
Reg. No./Substance:
0/Platelet Glycoprotein GPIIb-IIIa Complex

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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