Document Detail


The production of hypoallergenic wheat flour and the analysis of its allergy suppressive effects.
MedLine Citation:
PMID:  15630299     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We propose a novel method to produce hypoallergenic wheat flour suitable for patients allergic to wheat by using enzymatic fragmentation with cellulase and actinase. The hypoallergenic flour displayed potent inhibitory activity against allergen absorption and actively suppressed allergic reactions, probably inducing oral tolerance. The results suggest that hypoallergenic wheat flour has allergy-suppressive effects without inducing side effects.
Authors:
Jun Watanabe; Soichi Tanabe; Michiko Watanabe; Hiroshi Shinmoto; Kei Sonoyama
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BioFactors (Oxford, England)     Volume:  22     ISSN:  0951-6433     ISO Abbreviation:  Biofactors     Publication Date:  2004  
Date Detail:
Created Date:  2005-01-04     Completed Date:  2005-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807441     Medline TA:  Biofactors     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  295-7     Citation Subset:  IM    
Affiliation:
Food Function Division, National Food Research Institute, Japan. nabej@nfri.affrc.go.jp
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MeSH Terms
Descriptor/Qualifier:
Cellulase
Flour / adverse effects*
Food Handling / methods
Food Hypersensitivity / prevention & control*
Humans
Triticum / adverse effects*
Chemical
Reg. No./Substance:
EC 3.2.1.4/Cellulase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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