Document Detail


The prodromal questionnaire (PQ): preliminary validation of a self-report screening measure for prodromal and psychotic syndromes.
MedLine Citation:
PMID:  16276559     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study aims to establish preliminary validity of the Prodromal Questionnaire (PQ), a 92-item self-report screening measure for prodromal and psychotic symptoms. Adolescents and young adults (N = 113) referred to a prodromal psychosis research clinic completed the PQ and the Structured Interview for Prodromal Syndromes (SIPS [Miller, T.J., McGlashan, T.H., Woods, S.W., Stein, K., Driesen, N., Corcoran, C.M., Hoffman, R., Davidson, L., 1999. Symptom assessment in schizophrenic prodromal states. Psychiatric Quarterly 70(4), 273-287]), an interview with established validity for predicting future psychosis. When maximizing selection of true positive cases, scores on a subset of PQ items that assess positive symptoms predicted a concurrent prodromal or psychotic SIPS diagnosis with 90% sensitivity and 49% specificity. The PQ shows good preliminary validity in detecting individuals with an interview-diagnosed prodromal or psychotic syndrome, but it is less sensitive to the threshold between prodromal and full-blown psychosis.
Authors:
Rachel L Loewy; Carrie E Bearden; Jennifer K Johnson; Adrian Raine; Tyrone D Cannon
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Publication Detail:
Type:  Journal Article; Validation Studies    
Journal Detail:
Title:  Schizophrenia research     Volume:  79     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-07     Completed Date:  2006-02-24     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  117-25     Citation Subset:  IM    
Affiliation:
Department of Psychology, University of California, Los Angeles, 1285 Franz Hall. Box 951563, Los Angeles, CA 90095-1563, USA. rloewy@ucla.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Female
Humans
Male
Mass Screening / methods*
Observer Variation
Prevalence
Psychotic Disorders / diagnosis*,  epidemiology*
Questionnaires*
ROC Curve
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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