Document Detail

The problem of cycloplegia in the pediatric age group: a combination formula for refraction.
MedLine Citation:
PMID:  7391899     Owner:  NLM     Status:  MEDLINE    
Cycloplegic refraction and indirect ophthalmoscopy are essential to evaluation of the pediatric patient. Unfortunately, along with this practice occur the attendant risks of toxicity and the unpleasantness of instillation. The literature that documents the development of cycloplegic agents is often contradictory regarding efficacy and side effects. It is presented for perspective. We have found that efficacy and discomfort are inseparable; however, as with efficacy and toxicity they are directly related to the concentration used. The case is therefore made to use each agent in its minimal effective concentration and thereby minimize both discomfort and toxicity. Our combination of 1.3% cyclogyl, .167% mydriacil, and 1.6% phenylephrine accomplishes effective cycloplegia for refraction and indirect ophthalmoscopy, has a rapid onset and short duration, works reliably in dark irides, is accomplished in a single encounter with the patient, and exhibits none of the side effects of the individual agents in our series.
A R Caputo; R W Lingua
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric ophthalmology and strabismus     Volume:  17     ISSN:  0191-3913     ISO Abbreviation:  J Pediatr Ophthalmol Strabismus     Publication Date:    1980 Mar-Apr
Date Detail:
Created Date:  1980-09-28     Completed Date:  1980-09-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7901143     Medline TA:  J Pediatr Ophthalmol Strabismus     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  119-28     Citation Subset:  IM    
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MeSH Terms
Age Factors
Cyclopentolate / therapeutic use
Drug Combinations
Mydriatics / adverse effects,  therapeutic use*
Phenylephrine / therapeutic use
Refractive Errors / diagnosis*
Tropicamide / therapeutic use
Reg. No./Substance:
0/Drug Combinations; 0/Mydriatics; 1508-75-4/Tropicamide; 512-15-2/Cyclopentolate; 59-42-7/Phenylephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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