| A probiotics-containing biscuit modulates the intestinal microbiota in the elderly. | |
| | |
MedLine Citation:
|
PMID: 23364497 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Objectives: Evaluation of the impact of a biscuit containing the probiotics Bifidobacterium longum Bar33 and Lactobacillus helveticus Bar13 on the intestinal microbiota in the elderly. Design: Randomized double-blind placebo-controlled trial. Participants: Thirty-two elderly volunteers living in Italy. The group was composed of 19 women and 13 men aged between 71 and 88 years (mean 76). Intervention: Subjects were randomized in two groups consuming one dose of the probiotics-containing biscuit or placebo once a day for 30 days. Measurements: For each subject the intestinal microbiota was characterized using the phylogenetic microarray platform HTF-Microbi.Array before and after intervention. Results: Our data demonstrated that one-month consumption of a probiotics-containing biscuit was effective in redressing some of the age-related dysbioses of the intestinal microbiota. In particular, the probiotic treatment reverted the age-related increase of the opportunistic pathogens Clostridium cluster XI, Clostridium difficile, Clostridium perfringens, Enterococcus faecium and the enteropathogenic genus Campylobacter. Conclusion: The present study opens the way to the development of elderly-tailored probiotic-based functional foods to counteract the age-related dysbioses of the intestinal microbiota. |
| | |
Authors:
|
S Rampelli; M Candela; M Severgnini; E Biagi; S Turroni; M Roselli; P Carnevali; L Donini; P Brigidi |
Related Documents
:
|
2758707 - Morphometric study of salivary glands in primary sjögren's syndrome. 23248787 - Digestive symptoms in older adults: prevalence and associations with institutionalizati... 20819627 - Ningbo thyroid dysfunction prevalence study: a cross-sectional survey in an employees-c... 9302377 - Comparative screening for thyroid disorders in old age in areas of iodine deficiency, l... 22254287 - Pulse wave velocity normal levels in a uruguayan population: differences between 'adjus... 17208107 - Class ii subdivision malocclusion types and evaluation of their asymmetries. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The journal of nutrition, health & aging Volume: 17 ISSN: 1760-4788 ISO Abbreviation: J Nutr Health Aging Publication Date: 2013 |
Date Detail:
|
Created Date: 2013-01-31 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100893366 Medline TA: J Nutr Health Aging Country: France |
Other Details:
|
Languages: eng Pagination: 166-72 Citation Subset: IM |
Affiliation:
|
S. Rampelli, Department of Pharmaceutical Sciences, University of Bologna, Bologna, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Percutaneous endoscopic gastrostomy (PEG) tube feeding of nursing home residents is not associated w...
Next Document: A Multicentric Individually-Tailored Controlled Trial of Education and Professional Support to Nursi...