Document Detail

A probably familial saccular aneurysm of the anterior communicating artery in a neonate.
MedLine Citation:
PMID:  8252525     Owner:  NLM     Status:  MEDLINE    
A 32-day-old boy died of recurring cerebral hemorrhages starting on the 4th day of life. Autopsy disclosed a remittingly ruptured saccular aneurysm of the anterior communicating artery. A 7-day-old brother of his had previously died of recurring subarachnoid hemorrhages as well. The young age of the patient, the site of the aneurysm, and its probably familial occurrence make this case a unique one. Nonaneurysmatic basal cerebral arteries showed remarkable histological changes partly resembling those seen in fibromuscular dysplasia, some of them probably representing preaneurysmatic alterations. A known underlying systemic disease could not be found, and immunohistochemical detection of type III collagen revealed no identifiable deficiency.
K Kuchelmeister; R Schulz; M Bergmann; R Schwuchow; E Vollmer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  9     ISSN:  0256-7040     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1994-01-11     Completed Date:  1994-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  302-5     Citation Subset:  IM    
Institut für Neuropathologie, Universität, Münster, Germany.
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MeSH Terms
Aneurysm, Ruptured / genetics*,  pathology
Brain / pathology
Cerebral Arteries / pathology
Cerebral Hemorrhage / genetics,  pathology
Infant, Newborn
Intracranial Aneurysm / genetics*,  pathology

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