| A principal case of multiple lymphoid collision tumors involving both B-cell chronic lymphocytic leukemia and metastatic malignant melanoma. | |
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MedLine Citation:
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PMID: 20673534 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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B-cell chronic lymphocytic leukemia/small lymphocytic B-cell lymphoma (CLL/B-SLL) is a neoplasm of B-cell lymphocytes that occurs frequently in the older population as an asymptomatic elevation of the white blood cell count (WBC) and has a good overall prognosis. Malignant melanoma of the skin is a neoplasm derived from cutaneous melanocytes that frequently arises among the elderly and, depending on certain histopathologic features, may metastasize loco-regionally or distally. However, only one report describes synchronous presentation of these two malignancies within the same lymph node. In this report, we present the unique case of an 87-year-old male with a presumed history of indolent CLL/B-SLL, in which metastatic malignant melanoma and CLL/B-SLL both involved 112 of 145 dissected regional lymph nodes. Possible explanations regarding the mechanisms that can lead to this rare presentation of both CLL/B-SLL and melanoma in the same lymph nodes are discussed. |
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Authors:
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Aaron S Cantor; Stergios Moschos; Drazen M Jukic |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-07-15 |
Journal Detail:
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Title: Dermatology online journal Volume: 16 ISSN: 1087-2108 ISO Abbreviation: Dermatol. Online J. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-08-02 Completed Date: 2010-11-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610776 Medline TA: Dermatol Online J Country: United States |
Other Details:
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Languages: eng Pagination: 6 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Antigens, CD20 / analysis Antigens, CD79 / analysis Fatal Outcome Humans Leukemia, Lymphocytic, Chronic, B-Cell / complications, diagnosis*, pathology Lymph Nodes / pathology Male Melanoma / complications, diagnosis*, pathology Multiple Organ Failure / diagnosis, etiology, pathology Neoplasms, Multiple Primary / complications, diagnosis*, pathology Receptors, IgE / analysis Skin Neoplasms / complications, diagnosis*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD20; 0/Antigens, CD79; 0/Receptors, IgE |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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