| The primary structure of the hemoglobin of the Indian false vampire (Megaderma lyra, Microchiroptera). | |
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MedLine Citation:
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PMID: 3348887 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The hemoglobin of the Indian false vampire Megaderma lyra contains only one component. In this paper, we are presenting its primary structure. The globin chains were separated by high-performance liquid chromatography and the sequences determined by automatic liquid and gas phase Edman degradation of the chains and their tryptic peptides, as well as of the prolyl-peptides obtained by acid hydrolysis of the Asp-Pro bond in the alpha- and beta-chains. The alpha-chains show 23 and the beta-chains 20 exchanges compared with the human alpha- and beta-chains, respectively. In the alpha-chains, three exchanges involved alpha 1/beta 1 contacts. In the beta-chains one heme-and three alpha 1/beta 1 contacts are exchanged. The functional and systematic aspects of these replacements are discussed. |
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Authors:
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J G Sgouros; T Kleinschmidt; G Braunitzer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biological chemistry Hoppe-Seyler Volume: 369 ISSN: 0177-3593 ISO Abbreviation: Biol. Chem. Hoppe-Seyler Publication Date: 1988 Jan |
Date Detail:
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Created Date: 1988-05-10 Completed Date: 1988-05-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8503054 Medline TA: Biol Chem Hoppe Seyler Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 47-53 Citation Subset: IM |
Affiliation:
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Max-Planck-Institut für Biochemie, Abteilung Proteinchemie, Martinsried bei München. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acid Sequence Animals Chiroptera / blood* Globins / analysis Hemoglobins / isolation & purification* Molecular Sequence Data Peptide Fragments / isolation & purification Protein Conformation |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 0/Peptide Fragments; 9004-22-2/Globins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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