| The price of emergency contraception in the United States: what is the cost-effectiveness of ulipristal acetate versus single-dose levonorgestrel? | |
| | |
MedLine Citation:
|
PMID: 23040122 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Ulipristal acetate (UPA) is a novel form of emergency contraception (EC) that appears to be more effective than the prevailing method, single-dose levonorgestrel (LNG). This study examines the cost-efficacy of UPA compared with LNG. STUDY DESIGN: A decision-analytic model was developed to compare the cost-effectiveness of UPA versus LNG in preventing unintended pregnancy when taken within 120 h of unprotected intercourse. Univariate and bivariate sensitivity analyses, as well as Monte Carlo simulation and threshold analyses, were performed. RESULTS: Utilizing UPA instead of LNG would result in 37,589 fewer unintended pregnancies per 4,176,572 estimated US annual EC uses (UPA 54,295 pregnancies; LNG 91,884 pregnancies) and a societal savings of $116.3 million annually. Cost-effectiveness acceptability curve analyses suggest a 96% probability that UPA is more cost-effective at a willingness to pay $100,000 per quality-adjusted life year. CONCLUSIONS: UPA is cost-effective in preventing unintended pregnancy after unprotected intercourse. Efforts should be promoted to increase access to UPA. |
| | |
Authors:
|
Lisa L Bayer; Alison B Edelman; Aaron B Caughey; Maria I Rodriguez |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-10-4 |
Journal Detail:
|
Title: Contraception Volume: - ISSN: 1879-0518 ISO Abbreviation: Contraception Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-10-8 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0234361 Medline TA: Contraception Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR 97239, USA. Electronic address: bayerl@ohsu.edu. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: How does the number of oral contraceptive pill packs dispensed or prescribed affect continuation and...
Next Document: Hemoglobin measurement prior to initiating copper intrauterine devices: a systematic review.