| The prevention of prosthetic infection using a cross-linked albumin coating in a rabbit model. | |
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MedLine Citation:
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PMID: 9331043 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated the effects of a serum protein coating on prosthetic infection in 29 adult male rabbits divided into three groups: control, albumin-coated and uncoated. We used 34 grit-blasted, commercially pure titanium implants. Eleven were coated with cross-linked albumin. All the implants were exposed to a suspension of Staphylococcus epidermidis before implantation. Our findings showed that albumin-coated implants had a much lower infection rate (27%) than the uncoated implants (62%). This may be a useful method of reducing the infection of prostheses. |
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Authors:
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Y H An; J Bradley; D L Powers; R J Friedman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of bone and joint surgery. British volume Volume: 79 ISSN: 0301-620X ISO Abbreviation: J Bone Joint Surg Br Publication Date: 1997 Sep |
Date Detail:
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Created Date: 1997-11-06 Completed Date: 1997-11-06 Revised Date: 2010-11-10 |
Medline Journal Info:
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Nlm Unique ID: 0375355 Medline TA: J Bone Joint Surg Br Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 816-9 Citation Subset: AIM; IM |
Affiliation:
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Medical University of South Carolina, Charleston 29425-2239, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abscess
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pathology,
prevention & control* Animals Bone Substitutes / adverse effects, standards* Disease Models, Animal Male Materials Testing Prosthesis-Related Infections / pathology, prevention & control* Rabbits Random Allocation Serum Albumin, Bovine / standards* Staphylococcal Infections / pathology, prevention & control* Staphylococcus epidermidis* Titanium / adverse effects, standards* |
| Chemical | |
Reg. No./Substance:
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0/Bone Substitutes; 0/Serum Albumin, Bovine; 7440-32-6/Titanium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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