Document Detail

The prevention of low birthweight and its sequelae.
MedLine Citation:
PMID:  7845928     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Low birthweight and its components preterm birth and fetal growth retardation account for the vast majority of perinatal mortality and more than 50% of the long term neurologic morbidity. METHODS: Historical trends and the effectiveness of various interventions designed to improve pregnancy outcomes associated with low birthweight were evaluated in an attempt to define which future research efforts might be useful. RESULTS: Practices aimed at achieving a reduction in the low birthweight rate (the use of tocolytics, enhanced prenatal care, nutritional interventions) have not generally been successful or have not been widely utilized (smoking cessation programs). Practices aimed at improving low birthweight survival and reducing morbidity (group B streptococcus prophylaxis, maternal corticosteroids, surfactant use, newborn ventilation) have been responsible for most of the improvements in outcome. CONCLUSION: Continued effort into discovering effective practices for reducing low birthweight, for understanding the most appropriate methods of implementing practices known to be effective in reducing low birthweight, and refinement of practices known to reduce mortality and long term handicap in low birthweight babies should be major foci of prevention research.
R L Goldenberg
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Preventive medicine     Volume:  23     ISSN:  0091-7435     ISO Abbreviation:  Prev Med     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1995-03-09     Completed Date:  1995-03-09     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0322116     Medline TA:  Prev Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  627-31     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Alabama at Birmingham 35233-7333.
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MeSH Terms
Fetal Growth Retardation / etiology,  prevention & control*
Infant, Low Birth Weight*
Infant, Newborn
Obstetric Labor, Premature / etiology,  prevention & control*,  therapy
Risk Factors
Grant Support
282-92-0055//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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