Document Detail

The prevention of food allergy in children.
MedLine Citation:
PMID:  23324902     Owner:  NLM     Status:  Publisher    
PURPOSE OF REVIEW: This article reports recent advances in early nutritional strategies used in the prenatal/postnatal periods for preventing allergies in children. RECENT FINDINGS: Exclusive breastfeeding for 6 months is a desirable goal; however, with regard to allergy, the results of studies are inconsistent, showing a protective effect, no effect, or even a predisposing effect. For infants with a documented hereditary risk of allergy (i.e., an affected parent and/or sibling) who cannot be breastfed exclusively, dietary products with confirmed reduced allergenicity are recommended. Currently, there is no convincing scientific evidence that the avoidance or delayed introduction of potentially allergenic foods beyond 4-6 months reduces allergies in infants considered to be at increased risk for the development of allergic diseases or in those not considered to be at increased risk. The timing of n-3 long-chain polyunsaturated fatty acid supplementation may play a role in preventing early childhood allergy. Weak evidence from observational trials suggests a role of vitamins A, D, and E; zinc; fruit and vegetables; and a Mediterranean diet in the prevention of atopic disease. SUMMARY: Current evidence challenges earlier dogma. Thus, more research, preferentially from randomized controlled trials, is needed with regard to evaluating the efficacy and safety of all nutritional interventions for allergy prevention.
Hania Szajewska
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-14
Journal Detail:
Title:  Current opinion in clinical nutrition and metabolic care     Volume:  -     ISSN:  1473-6519     ISO Abbreviation:  Curr Opin Clin Nutr Metab Care     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9804399     Medline TA:  Curr Opin Clin Nutr Metab Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Paediatrics, The Medical University of Warsaw, Warsaw, Poland.
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