Document Detail

The prevention of extra cardiac conduit obstruction: an experimental study.
MedLine Citation:
PMID:  6221159     Owner:  NLM     Status:  MEDLINE    
Acquired right ventricular (RV) extracardiac conduit (ECC) obstruction was studied in an animal model. A 16 mm woven Dacron tube graft was inserted between the right ventricle (RV) and main pulmonary artery (PA) in 18 adult mongrel dogs followed by pulmonary artery occlusion with a Dacron tape. In 9 dogs, the RV anastomosis was maintained with a 16 mm Dacron covered polypropylene stent. The remaining 9 animals with direct suture attachment of the graft to the myocardium served as controls. Cardiac output and transconduit resistance were measured at operation, 6 months, and 1 year. The cardiac output remained the same in both groups. Animals with stented ECC showed little change in transconduit resistance and had a widely patent RV anastomosis at 1 year. Unstented conduits had increased transconduit resistance at 6 months and 1 year (P less than 0.002). Postmortem examination showed fibromuscular ingrowth of the ventricular anastomosis to be the site of the acquired obstruction in unstented extracardiac conduits. The inclusion of a rigid stent in RV-ECC may warrant clinical application to prevent fibromuscular ingrowth and late RV anastomotic obstruction.
A C Fiore; P S Peigh; N J Sears; W P Deschner; J W Brown
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of surgical research     Volume:  34     ISSN:  0022-4804     ISO Abbreviation:  J. Surg. Res.     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-06-23     Completed Date:  1983-06-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0376340     Medline TA:  J Surg Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  463-72     Citation Subset:  IM    
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MeSH Terms
Blood Vessel Prosthesis*
Cardiac Output
Heart Defects, Congenital / surgery*
Heart Ventricles / surgery
Polyethylene Terephthalates
Prosthesis Design
Pulmonary Artery / surgery
Vascular Resistance
Reg. No./Substance:
0/Polyethylene Terephthalates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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