Document Detail

The prevalence and risk factors of an abnormal ankle-brachial index in patients with type 2 diabetes.
MedLine Citation:
PMID:  22078109     Owner:  NLM     Status:  Publisher    
Objectives:  The aim of this study was to examine ankle-brachial index(ABI) abnormality and their related risk factors in patients with type 2 diabetes. Methods:  An ABI was obtained in 3924 outpatients in the diabetes centre, 306(th) Hospital of PLA during the period of September 2003 to June 2010. Patients' profile and laboratory data were collected. The risk factors for abnormal ABI were determined using univariate and stepwise logistic regression analysis. Results:  ABI was normal in 93.1%, low in 5.2%, and high in 1.7% of patients. Elderly patients (≧65years) had a higher prevalence of low ABI(12.2%)compared with younger patients(<65years) (3.6%).Using normal ABI as referent, low ABI in younger patients was independently associated with HbA1c, urine albumin/creatinine ratio, diabetic peripheral neuropathy, diabetic retinopathy and cerebrovascular disease. Low ABI in elderly patients was independently associated with age, smoking, glycosylated haemoglobin, uric acid, total cholesterol, diabetic peripheral neuropathy, diabetic retinopathy, diabetic nephropathy and cerebrovascular disease. High ABI in younger patients was associated with male. Conclusions:  The prevalence of abnormal ABI was high in patients with type 2 diabetes, especially in elderly patients. Early identification and intensive treatments are needed to improve quality of life and the overall prognosis of patients with type 2 diabetes.
Xiang Li; Yu-Zheng Wang; Xiao-Ping Yang; Zhang-Rong Xu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-12
Journal Detail:
Title:  Journal of diabetes     Volume:  -     ISSN:  1753-0407     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101504326     Medline TA:  J Diabetes     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Ruijin Hospital and Blackwell Publishing Asia Pty Ltd.
Diabetes Center, The PLA 306th Hospital, Beijing 100101, China.
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