| The prevalence of pulmonary embolism in chronically paralyzed subjects: a review of available evidence. | |
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MedLine Citation:
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PMID: 22158255 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Study design:Qualitative systematic review.Objectives:To examine the validity of the prevailing notion that pulmonary embolism (PE) is rare in the chronic spinal cord injury (SCI) population.Setting:USA.Methods:Review surveys of adult SCI subjects >2 months after injury in which PE has been looked for and its prevalence estimated.Results:A total of 16 surveys of chronic SCI subjects published between 1956 and 2009 offered data on PE prevalence. Two autopsy surveys, 178 subjects paralyzed >2 months, revealed no PE. Eleven surveys of the cause of death, 3193 subjects paralyzed 1-25 years, revealed PE in 2.1%. Two surveys of survivors of SCI, 5761 subjects paralyzed 1-25 years, revealed PE in 0.4%. Our survey of 112 subjects paralyzed 1-50 years before death, revealed PE in 21 (18.7%), based on autopsy, imaging, clinical and electrocardiographic evidence. In 7 (33%) of the 21 subjects with PE, pulmonary hypertension by transthoracic echocardiography was detected, indicating recurrent and/or unresolved PE.Conclusion:PE is not infrequent in the chronic SCI subject; but its presentation may be subclinical; and its apparent recurrence may lead to pulmonary hypertension.Spinal Cord advance online publication, 13 December 2011; doi:10.1038/sc.2011.154. |
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Authors:
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J H Frisbie; G V R K Sharma |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-13 |
Journal Detail:
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Title: Spinal cord Volume: - ISSN: 1476-5624 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9609749 Medline TA: Spinal Cord Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Medical Service, Boston Veterans Affairs Healthcare System, St Paul, MN, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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