Document Detail

The prevalence and predictors of atrial fibrillation in hemodialysis patients.
MedLine Citation:
PMID:  20215836     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The aim of this study was to determine the prevalence of atrial fibrillation in long-term hemodialysis patients and to identify clinical and echocardiographic risk factors. STUDY DESIGN: The study included 183 patients (93 males, 90 females; mean age 52+/-17 years) who had been on long-term hemodialysis treatment (mean 41.6+/-39.8 months) and had preserved systolic function. Atrial fibrillation was determined electrocardiographically and the patients were divided into two groups depending on the presence or absence of atrial fibrillation. Conventional and tissue Doppler echocardiographic examinations were performed on interdialytic days. Clinical, laboratory, and echocardiographic parameters were compared. RESULTS: Twenty-four patients (13.1%) had atrial fibrillation. Patients with atrial fibrillation significantly differed in terms of higher age (64.9+/-9.8 vs. 49.9+/-16.6 years; p<0.001), higher frequency of coronary artery disease (37.5% vs. 10.7%; p=0.008), and lower serum albumin level (3.6+/-0.4 vs. 3.9+/-0.5 mg/dl; p=0.015). Echocardiographic examination showed significantly increased left and right atrial diameters (p<0.05), higher incidence of mitral and/or aortic calcification (p=0.033), increased systolic pulmonary artery pressure (38.1+/-6.1 vs. 28.5+/-5.5 mmHg, p<0.001) and E/E' ratio (11.8+/-3.8 vs. 8.8+/-4.7, p=0.008) in patients with atrial fibrillation. In multivariate logistic regression analysis, age (OR 1.09; 95% CI 1.00-1.17; p=0.036) and right atrial diameter (OR 1.19; 95% CI 1.05-1.35; p=0.008) were independent risk factors for the development of atrial fibrillation. CONCLUSION: Our findings highlight age and right atrial diameter as independent predictors of atrial fibrillation in hemodialysis patients. In addition, the E/E' ratio and pulmonary artery pressure may be considered new risk factors of atrial fibrillation in this population.
G?rkan Acar; Ahmet Ak?ay; Ekrem Do?an; Ismet Onder I?ik; Abdullah S?kmen; G?lizar S?kmen; Hayriye Sayarlio?lu; Sedat K?ro?lu; Alper Bu?ra Nacar; Cemal Tuncer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  T?rk Kardiyoloji Derne?i ar?ivi : T?rk Kardiyoloji Derne?inin yay?n organ?d?r     Volume:  38     ISSN:  1016-5169     ISO Abbreviation:  Turk Kardiyol Dern Ars     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-06-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426239     Medline TA:  Turk Kardiyol Dern Ars     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  8-13     Citation Subset:  IM    
Department of Cardiology, Medicine Faculty of Kahramanmara? S?t?? Imam University, Kahramanmara?, Turkey.
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MeSH Terms
Atrial Fibrillation / epidemiology*,  physiopathology,  ultrasonography
Coronary Disease / complications
Diabetes Complications / classification
Heart Atria / physiopathology,  ultrasonography
Hypertension / complications
Middle Aged
Renal Dialysis / adverse effects*

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