| The prevalence of metabolic syndrome and its components in two main types of primary aldosteronism. | |
| | |
MedLine Citation:
|
PMID: 20574447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Metabolic syndrome (MS) is frequent clinical condition in patients with hypertension. Primary aldosteronism (PA) is a common form of secondary hypertension. This study was aimed at investigating the prevalence of the MS and its components in the two major forms of PA, in unilateral aldosterone-producing adenoma (APA) and bilateral aldosterone overproduction because of idiopathic hyperaldosteronism (IHA). The diagnosis of the particular form of PA was based on adrenal venous sampling and/or successful surgery confirmed by histopathological examination. We analyzed clinical and laboratory data from 100 patients with PA (50 patients with IHA and 50 patients with APA) and from 90 patients with essential hypertension (EH). Metabolic profiles of patients with bilateral form of PA (because of IHA) were similar to EH, but differed from those in patients with unilateral form of PA (APA). The prevalence of the MS (62% in IHA, 34% in APA and 56% in EH), the body mass index value (30±4 kg m(-2) in IHA, 27±5 kg m(-2) in APA and 29±5 kg m(-2) in EH) and triglycerides levels (1.9±0.9 mmol l(-1) in IHA,1.4±0.8 mmol l(-1) in APA and 2.01±1.39 mmol l(-1) in EH) were all significantly (P<0.05) higher in IHA compared with APA patients. Metabolic profile of patients with bilateral form of PA (because of IHA) is similar to EH in contrast to unilateral form of PA (APA). |
| | |
Authors:
|
Z Somlóová; J Widimský; J Rosa; D Wichterle; B Strauch; O Petrák; T Zelinka; J Vlková; M Masek; J Dvoráková; R Holaj |
Related Documents
:
|
3531037 - Converting enzyme inhibitors for the treatment of hypertension in the elderly. 11124317 - Recurrence of idiopathic intracranial hypertension after weight loss: the carrot craver. 799567 - Treatment of severe and moderate hypertension with minoxidil: experience in twenty-eigh... 7924177 - L-carnitine adjuvant therapy in essential hypertension. 7054027 - Gastric mucosal prostaglandin e levels in patients with gastric ulcer disease and carci... 18474887 - Age-related pulmonary crackles (rales) in asymptomatic cardiovascular patients. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-06-24 |
Journal Detail:
|
Title: Journal of human hypertension Volume: 24 ISSN: 1476-5527 ISO Abbreviation: J Hum Hypertens Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-16 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8811625 Medline TA: J Hum Hypertens Country: England |
Other Details:
|
Languages: eng Pagination: 625-30 Citation Subset: IM |
Affiliation:
|
Third Department of Internal Medicine--Center for Hypertension, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic. zsomloova@seznam.cz |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenoma
/
blood,
diagnosis,
epidemiology* Adrenal Gland Neoplasms / blood, diagnosis, epidemiology* Adult Aldosterone / blood Biological Markers / blood Blood Pressure Body Mass Index Czech Republic / epidemiology Female Humans Hyperaldosteronism / blood, diagnosis, epidemiology*, physiopathology Hyperlipidemias / blood, diagnosis, epidemiology*, physiopathology Hypertension / blood, diagnosis, epidemiology*, physiopathology Male Metabolic Syndrome X / blood, diagnosis, epidemiology* Middle Aged Prevalence Retrospective Studies Risk Assessment Risk Factors Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Triglycerides; 52-39-1/Aldosterone |
| Comments/Corrections | |
Comment In:
|
J Hum Hypertens. 2010 Oct;24(10):623-4
[PMID:
20631739
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Indication-specific 6-h systolic blood pressure thresholds can approximate 24-h determination of blo...
Next Document: Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers.