Document Detail

The prevalence of laryngeal pseudosulcus among Japanese patients with laryngopharyngeal reflux related symptoms.
MedLine Citation:
PMID:  15882824     Owner:  NLM     Status:  MEDLINE    
Infraglottic edema extending from the anterior commissure to the posterior larynx, called the laryngeal pseudosulcus, may have some value in the diagnosing of laryngopharyngeal reflux (LPR). The purpose of this study is to evaluate the prevalence, sensitivity and specificity of this finding among Japanese patients with LPR-related symptoms. Forty-three patients diagnosed as LPR based on their symptoms and 42 control patients without LPR were enrolled. The presence of pseudosulcus was determined with transnasal fiberoptic laryngoscopy. Thirty-seven of the 43 patients with LPR and 13 of the 42 control patients had evidence of laryngeal pseudosulcus (p<0.001). The sensitivity and specificity of pseudosulcus in the symptom-based diagnosis of LPR are 86 and 69%, respectively. This study shows that laryngeal pseudosulcus is highly correlated with LPR-related symptoms. The presence of this finding is suggestive of LPR.
Nobuhiko Oridate; Yasushi Mesuda; Noriko Nishizawa; Mika Mori; Yasushi Furuta; Hiroshi Takeda; Satoshi Fukuda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Auris, nasus, larynx     Volume:  32     ISSN:  0385-8146     ISO Abbreviation:  Auris Nasus Larynx     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-05-10     Completed Date:  2005-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708170     Medline TA:  Auris Nasus Larynx     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  39-42     Citation Subset:  IM    
Department of Otolaryngology-Head and Neck Surgery, Hokkaido University, Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan.
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MeSH Terms
Asian Continental Ancestry Group / statistics & numerical data*
Esophagitis / ethnology
Gastroesophageal Reflux / ethnology*,  physiopathology*
Laryngoscopy / methods
Larynx / abnormalities*,  physiopathology*
Middle Aged
Pharynx / physiopathology*
Severity of Illness Index

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