| The prevalence of hepatitis B surface antigen and antibody in home-reared individuals with Down syndrome. | |
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MedLine Citation:
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PMID: 1838813 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We examined 180 noninstitutionalized persons with Down syndrome for the presence of both hepatitis B surface antigens and antibodies to hepatitis B surface antigen. Two of the 180 subjects with Down syndrome had a positive test. One patient was hepatitis B surface antigen positive and the other was found to have antibodies to hepatitis B surface antigen. Also, 2 of the 155 individuals in the comparison group tested positive for hepatitis B surface antigen. Thus, we did not observe an increased prevalence of hepatitis B surface antigen or antibody in the study group and there was no significant difference between the Down syndrome and comparison groups. This is in contrast to many studies that originated in residential facilities where an increased number of persons with Down syndrome were found to have hepatitis B surface antigenemia. The related public health concerns are discussed. |
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Authors:
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S M Pueschel; H C Bodenheimer; P Giesswein; M K Dean |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Research in developmental disabilities Volume: 12 ISSN: 0891-4222 ISO Abbreviation: Res Dev Disabil Publication Date: 1991 |
Date Detail:
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Created Date: 1992-04-01 Completed Date: 1992-04-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8709782 Medline TA: Res Dev Disabil Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 243-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Rhode Island Hospital. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Child, Preschool Cohort Studies Down Syndrome / immunology* Female Hepatitis B / immunology*, transmission Hepatitis B Antibodies / analysis* Hepatitis B Surface Antigens / analysis* Home Nursing* Humans Infant Institutionalization Male |
| Chemical | |
Reg. No./Substance:
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0/Hepatitis B Antibodies; 0/Hepatitis B Surface Antigens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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