Document Detail


The prevalence of congenital malaria among neonates with suspected sepsis in Calabar, Nigeria.
MedLine Citation:
PMID:  18453488     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the prevalence of congenital malaria among neonates with suspected sepsis and its outcome at the University of Calabar Teaching Hospital, Calabar, Nigeria. All in-born neonates admitted to the newborn unit with clinical features suggestive of sepsis were recruited. They were screened for bacterial sepsis and malaria. The mothers of the neonates that had parasitaemia were further screened for malaria and anaemia. A total of 546 in-born neonates were admitted to the neonatal unit and 202 (37%) presented with clinical signs suggested of sepsis. Of these, 71 babies (35% of 202 or 13% of the total in-born nursery admissions) had congenital malaria and 14 also had sepsis. Sixty-three (88.7%) of the parasitaemic babies were delivered by mothers who received antenatal care at our centre. Eighty-six percent of the mothers of the 71 babies also had the malaria parasite in their blood. The majority (67%) of the 71 mothers were gravidae 2 and below. Thirty (42.3%) of the affected neonates were anaemic and 5 (7%) of them required a blood transfusion. Congenital malarial is not uncommon in Calabar among babies with suspected sepsis. It appears that the antenatal chemoprophylaxis with pyrimethamine (25 mg weekly) currently used for malaria in our centre no longer protects the mother and fetus. An alternative is needed in order to stem maternal, fetal and neonatal morbidity and wastage. Babies with features of sepsis should be routinely screened for malaria.
Authors:
A D Ekanem; M U Anah; J J Udo
Related Documents :
20525358 - Predictors of positive blood culture and deaths among neonates with suspected neonatal ...
7039518 - Gallbladder distension in septic neonates.
20973858 - Changing trends in newborn sepsis in sagamu, nigeria: bacterial aetiology, risk factors...
19925368 - Reliability of procalcitonin in neonatology. experience in 59 preterm newborns.
12675178 - Nutrition education and infant growth in rural indian infants: narrowing the gender gap?
18300148 - Anterior dynamic ultrasound and graf's examination in neonatal hip instability.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tropical doctor     Volume:  38     ISSN:  0049-4755     ISO Abbreviation:  Trop Doct     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-05-05     Completed Date:  2008-07-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1301706     Medline TA:  Trop Doct     Country:  England    
Other Details:
Languages:  eng     Pagination:  73-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, College of Medical Sciences, University of Calabar, Calabar, Nigeria. ediomoanah@yahoo.co.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anemia / complications
Animals
Bacteremia / complications,  epidemiology,  microbiology
Female
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical
Malaria, Falciparum / complications,  congenital*,  epidemiology*,  parasitology
Male
Nigeria / epidemiology
Parasitemia / complications,  epidemiology,  parasitology
Plasmodium falciparum / isolation & purification*
Pregnancy
Pregnancy Complications, Parasitic / epidemiology,  parasitology
Prevalence
Prognosis
Sepsis* / complications,  epidemiology,  microbiology,  parasitology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Chikungunya: a review.
Next Document:  Causes of gas gangrene seen at the University of Nigeria Teaching Hospital, Enugu, Nigeria.