Document Detail

The prevalence of cholelithiasis in sickle cell disease as diagnosed by ultrasound and cholecystography.
MedLine Citation:
PMID:  492833     Owner:  NLM     Status:  MEDLINE    
Gallbladder disease is known to be increased in sickle cell disease (SS). The prevalence of cholelithiasis in children with SS has been reported as 10% to 37%. Gallbladder ultrasound, cholecystography, and/or abdominal radiography were used to evaluate 31 patients aged 2 to 18 years with no systematic evidence of gallbladder disease for cholelithiasis, Overall prevalence of gallstones was found to be 29%. Cholelithiasis was detected in children as young as 4 years of age. Prevalence below the age of 10 years and above the age of 10 years was found to be 11% and 55% respectively. The increased prevalence of cholelithiasis in children with sickle cell disease suggests the use of diagnostic ultrasonography as a routine screening procedure.
B S Lachman; J Lazerson; R J Starshak; F M Vaughters; S L Werlin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  64     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1979 Nov 
Date Detail:
Created Date:  1979-12-29     Completed Date:  1979-12-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  601-3     Citation Subset:  AIM; IM    
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MeSH Terms
Anemia, Sickle Cell / blood,  complications*
Child, Preschool
Cholelithiasis / complications*,  diagnosis
Erythrocyte Count
Hemoglobins / analysis
Reg. No./Substance:

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